Confirm creatinine clearance is greater than or equal to 35 mL/min
Confirm serum calcium is within normal range
Instruct patient to drink fluids, such as water, within a few hours prior to infusion to ensure adequate hydration
2. Instructions for use
Assemble supplies
Obtain IV access (use of saline lock recommended for infusion)
Prepare Reclast, open vent cap and prime tubing
Infuse over no less than 15 minutes over a constant infusion rate
Remove IV catheter and dispose of properly
3. Instructions for patients after infusion
All patients should be instructed on the importance of calcium and vitamin D supplementation. Please refer to Reclast full Prescribing Information for recommendations
In clinical trials, transient postdose symptoms (fever, myalgia, flu-like symptoms, headache and arthralgia) were the most common adverse events
The majority occurred within 3 days of infusion and most resolved within 3 days of onset but could take up to 7–14 days
Treatment with acetaminophen can reduce the incidence of postdose symptoms
Reclast is provided in ready-to-use plastic bottles as 5 mg doses in 100 mL aqueous solution. A single dose should not exceed 5 mg.
